Published Researchs

-Catalyzed Synthesis of 4H-benzo[4,5]thiazolo[3,2-a]pyrimidin4-ones: Molecular Docking Studies and Anti-proliferative Activities Against HepG2 Hepatocellular Carcinoma CellsAsian Journal of Organic ChemistryOrganic Chemistry2024  Visit URL
In silico and in vitro evaluation of novel carbothioamide-based and heterocyclic derivatives of 4-(tert-butyl)-3-methoxybenzoic acid as EGFR tyrosine kinase allosteric site inhibitorsResults in ChemistryAnticancer drugs2024  Visit URL
New Indole-6-Carboxylic Acid Derivatives as Multi-Target Antiproliferative Agents: Synthesis, in Silico Studies, and Cytotoxicity EvaluationChemistry & BiodiversityAnticancer drugs2024  Visit URL
Role and Function of Receptor Tyrosine Kinases in BRAF Mutant CancersReceptorsCancer Bioliogy2024  Visit URL
Chemokine Receptor Antagonists Prevent and Reverse Cofilin-Actin Rod Pathology and Protect Synapses in Cultured Rodent and Human iPSC-Derived NeuronsBiomedicinesNeurodegeneration2024  Visit URL
Novel 5-Bromoindole-2-Carboxylic Acid Derivatives as EGFR Inhibitors: Synthesis, Docking Study, and Structure-Activity RelationshipAnti-Cancer Agents in Medicinal ChemistryCancer biology2023  Visit URL
New Combretastatin Analogs as Anticancer Agents: Design, Synthesis, Microtubules Polymerization Inhibition, and Molecular Docking StudiesChemistry and BiodiversityCancer biology2023  Visit URL
On the Performance of Green Desymmetrization Methods toward Bioactive Cephalostatin AnalogsCurrent Medicinal ChemistryCancer biology2023  Visit URL
Design, Synthesis, in Silico and in Vitro Evaluation of New Combretastatin A-4 Analogs as Antimitotic Antitumor AgentsMedicinal ChemistryCancer biology2023  Visit URL
New Tolfenamic Acid Derivatives with Hydrazine-1-Carbothioamide and 1,3,4-Oxadiazole Moieties Targeting VEGFR: Synthesis, in silico Studies, and in vitro Anticancer AssessmentMedicinal Chemistry ResearchCancer biology2023  Visit URL
Characterization of a Human Neuronal Culture System for Study of Cofilin–Actin Rod PathologyBiomedicinesNeurodegeneration2023  Visit URL
Antitumor activity of the new tyrphostin briva against BRAFV600E-mutant colorectal carcinoma cellsInvestigational New DrugsCancer2023  Visit URL
Design, Synthesis, and Molecular Docking Studies of 5- Bromoindole-2-Carboxylic Acid Hydrazone Derivatives: In Vitro Anticancer and VEGFR-2 Inhibitory EffectsChemistrySelectCancer biology2022  Visit URL
Editorial: Molecular mechanisms of epithelial-mesenchymal transition in cancer metastasisFrontiers in OncologyCancer biology2022  Visit URL
Morphological signatures of actin organization in single cells accurately classify genetic perturbations using CNNs with transfer learningSoft MatterCancer biology2022  Visit URL
New Niflumic Acid Derivatives as EGFR Inhibitors: Design, Synthesis, In silico Studies, and Anti-proliferative AssessmentMedicinal ChemistryCancer biology2022  Visit URL
Synthesis, Molecular Docking Studies, and In Vitro Anticancer Evaluation of Novel Tolfenamic Acid DerivativesLetters in Drug Design & DiscoveryCancer biology2022  Visit URL
Synthesis, docking study, and structureactivity relationship of novel niflumic acid derivatives acting as anticancer agents by inhibiting VEGFR or EGFR tyrosine kinase activitiesPharmaciaCancer biology2022  Visit URL
Synthesis, docking study, and structure activity relationship of novel anti-tumor 1, 2, 4 triazole derivatives incorporating 2-(2, 3- dimethyl aminobenzoic acid) moietyPharmaciaCancer biology2022  Visit URL
The role of activated androgen receptor in cofilin phospho-regulation depends on the molecular subtype of TNBC cell line and actin assembly dynamicsPLOS ONECancer biology2022  Visit URL
Vitamin B12 enhances the antitumor activity of 1,25-dihydroxyvitamin D3 via activation of caspases and targeting actin cytoskeletonTumor Biology Molecular2022  Visit URL
A novel derivative of picolinic acid induces endoplasmic reticulum stress-mediated apoptosis in human non-small cell lung cancer cells: synthesis, docking study, and anticancer activityPharmaciaCancer biology2021  Visit URL
Cofilin and Actin Dynamics: Multiple Modes of Regulation and Their Impacts in Neuronal Development and DegenerationCellsNeurodegeneration2021  Visit URL
New picolinic acid derivatives: Synthesis, docking study and anti-EGFR kinase inhibitory effectMaterials Today: ProceedingsCancer biology2021  Visit URL
Synthesis, docking study, and in-vitro anti-cancer evaluation of new triazole derivatives of flufenamic acidMaterials Today: ProceedingsCancer biology2021  Visit URL
Synthesis and Cytotoxic Activity of Some New Bipyrazole Derivativessis and Cytotoxic Activity of Some New Bipyrazole DerivativesHeterocyclesCancer Biology2020  Visit URL
Alu Repeat Polymorphism in the Tissue Plasminogen Activator (t-PA) Gene, Seminal t-PA Concentration and Male Fertility Impairment.International Journal of Reproductive BiomedicineFertility2020  Visit URL
Age of the Donor Affects the Nature of in vitro Cultured Human Dental Pulp Stem CellsSaudi Dental JournalDevelopmental Biology2020  Visit URL
BiologicBiological Activity and Apoptotic Signaling Pathway of C11- Functionalized Cephalostatin 1 Analoguesal Activity and Apoptotic Signaling Pathway of C11- Functionalized Cephalostatin 1 AnaloguesSteroidsCancer Biology2020  Visit URL
Alu DNA Polymorphism of Human Tissue Plasminogen Activator (tPA) Gene in Jordanian Type 1 and Type 2 Diabetic PatientsIranian Biomedical JournalMolecular Biology2019  Visit URL
Cetyl-Alcohol-Reinforced Hollow Fiber Solid/ Liquid Phase Microextraction and HPLC-DAD Analysis of Ezetimibe and Simvastatin in Human Plasma and Urine.Biomedical ChromatographyChromatography2019  Visit URL
Factors Influencing Successful Pregnancy Outcomes in IVF Cycles among Jordanian Infertile CouplesClinical and Experimental Obstetrics & GynecologyFertility2018  Visit URL
Deletion of the Alu Repeat in the Tissue Plasminogen Activator (tPA) Gene is Protective for Breast CancerInternational Journal of Cancer ResearchCancer Biology2018  Visit URL
Tahtamouni L, Nawasreh M, Al-Mazaydeh Z, Al-Khateeb R, Abdellatif R, Bawadi R, Bamburg J, Yasin S. Cephalostatin 1 Analogues Activate Endoplasmic Reticulum Stress Apoptotic Signaling PathwayEuropean Journal of Pharmacology Cancer research2018  Visit URL
The Cellular and Molecular Effects of the Androgen Receptor Agonist, Cl-4AS-1, on Breast Cancer CellsEndocrine ResearchCancer Biology2018  Visit URL
Low Rate of Cervical Cancer among Women with Rising Incidence of Cervical Cytological Abnormalities. The Unlearnt LessonEuropean Journal of Gynaecological OncologyCancer Biology2018  Visit URL
The cellular and molecular effects of the androgen receptor agonist, Cl-4AS-1, on breast cancer cellsEndocrine ResearchCancer Biology2018  Visit URL
Freij MA, Khadra MM, Abu Farsakh HA, Saleh HH, Ijmail AA, Rahal BO, Waldali MH, Tahtamouni LH. (2017). Type Specific Prevalence of Human Papillomavirus among Women with Abnormal Cytology in Jordan. .European Journal of Gynaecological Oncology Cancer research2017  Visit URL
Tahtamouni LH, Abdellatif RN, Al-Khateeb RA, Al-Mazaydeh ZA, Yasin SR, Al-Gharabli SI, Elkarmi AZ. (2017). Taraxacum officinale Root Aqueous Extract Impairs the Expression of Spermatogonial Stem Cell Markers in Adult Rat. Tropical Journal of Pharmaceutical Research Reproductive biology2017  Visit URL
Khadra MM, Freij MA, Al-Mazaydeh Z, Saleh S, Kilani R, Tahtamouni LH. (2017). Factors Influencing Successful Pregnancy Outcomes in IVF Cycles among Jordanian Infertile Couples. Clinical and Experimental Obstetrics & Gynecology Reproductive biology2017  Visit URL
Nawasreh MM, Tahtamouni LH. (2017). The Effect of Orchis anatolica Leaves on Reproductive System-An in Vivo Study. International Journal of Pharma Medicine and Biological SciencesReproductive biology2017  Visit URL
Freij MA, Khadra MM, Abu Farsakh HA, Saleh HH, Ijmail AA, Rahal BO, Waldali MH, Najeeb NS, Tahtamouni LT. (2017). Low Rate of Cervical Cancer among Women with Rising Incidence of Cervical Cytological Abnormalities. The Unlearnt Lesson.European Journal of Gynaecological OncologyCancer research2017  Visit URL
Abu Safieh KA, Tabba HD, AlMasri HA, Bawadi RM, Boudjelal FM, Tahtamouni LH. (2016). Novel Palladium(II) and Platinum(II) Complexes with a Fluoro Piperazinyl Based Ligand Exhibiting High Cytotoxicity and Anticancer Activity in vitro. Journal of Chemistry Cancer Biology2016  Visit URL
Khadra MM, Freij MA, Al-Ramahi MQ, Al-Jamal AY, Thekrallah FM, Tahtamouni LH. (2016). Human Chorionic Gonadotropin Cut-off Value Determined by Receiver Operating Characteristic Curve Analysis is Useful But Not Absolute for Determining Pregnancy Outcomes. Middle East Fertility Society Journal Fertiltity2016  Visit URL
Yasin S, Tahtamouni LH, Al-Khateeb R, Abdellatif R, Al-Mazaydeh Z, Al-Emerieen A,Al-Khateeb H, Al-Hadidi A-H. (2016). Screening for CYP2C19 Gene Variants in a Healthy Jordanian Population. Tropical Journal of Pharmaceutical ResearchMolecular biology2016  Visit URL
Tahtamouni LH, Al-Khateeb R, Abdellatif R, Al-Mazaydeh Z, Yasin S, Al-Gharabli S, Elkarmi A. Anti-spermatogenic Activities of Taraxacum officinale Leaves Aqueous Extract. Veterinary Research ForumFertility2016  Visit URL
Mustafa EH, Mahmoud HT, Al-Hudhud MY, Abdalla MY, Ahmad IM, Yasin SR, Elkarmi AZ, Tahtamouni LH. (2015) 2-Deoxy-D-glucose Synergizes with Doxorubicin or L-Buthionine Sulfoximine to Reduce Adhesion and Migration of Breast Cancer Cells. Asian Pac J Cancer Prev Cancer Biology2015  Visit URL
Yasin SR, Tahtamouni LH, Najeeb NS, Issa NM, Al-Mazaydeh ZA, Alfaouri AA. (2014) Genomic Integrity of the Y Chromosome Sequence-tagged Sites in Infertile and Down Syndrome Jordanian males. AndrologiaReproductive biology2014  Visit URL
Hussein AA, Bawadi RM, Tahtamouni LH, Frangoul H, Elkarmi AZ. (2014) Feasibility of Collecting Umbilical Cord Blood in Jordan and the Effect of Maternal and Neonatal Factors of Hematopoietic Stem Cell Content.Meditterr J Hematol Infect Dis Stem cell research2014  Visit URL
Al-Zube L, Al-Momani T, Al-Bataineh O, Tahtamouni LH. (2013). In vitro Characterization of Calcium Salts as Delivery Vehicles for Insulin. Journal of Biomimetics, Biomaterials & Tissue EngineeringTissue engineering2013  Visit URL
Tahtamouni LH. (2013) Use of Anabolic Androgenic Steroids in Jordan: Mini- Review. Jordan Journal of Biological Sciences Fertility2013  Visit URL
Tahtamouni LH, Shaw AE, Hasan MH, Yasin SR, Bamburg JR. (2013) Non-overlapping Activities of ADF and Cofilin-1 During the Migration of Metastatic Breast Tumor Cells. BMC Cell Biology Cancer research2013  Visit URL
Al-Noaimi M, Abu-Surrah A, Tahtamouni LH. (2012). Palladium (II) Complexes Incorporating Phenylazo Arylmethine Ancillary Ligands: Synthesis, Spectral and Antitumor Activity. Arabian Journal of ChemistryCancer research2012  Visit URL
Kadir S, Astin J, Tahtamouni LH, Martin P, Nobes C. (2011). Microtubule Remodeling is Required for the Front-Rear Polarity Switch During Contact Inhibition of Locomotion. Journal of Cell Science 124(Pt 15):2642-2653.Cancer Biology2011  Visit URL
Tahtamouni, LH, Alqurna NM, Al-Hudhud MY, Al-Hajj HA. (2011) Dandelion (Taraxacum officinale) Decreases Male Rat Fertility in vivo. J Ethnopharm Fertility2011  Visit URL
Tahtamouni LH, Bamburg JR. (2011) Redundant and Non-Redundant Functions of ADF and Cofilin in Metastasis.Jordan Journal of Biological Sciences Cancer research2011  Visit URL
Tahtamouni LH, Mustafa NH, Hassan IM, Ahmad IM, Abdalla MY. (2010) Nandrolone Decanoate Administration to Male Rats Induces Oxidative Stress, Seminiferous Tubules Abnormalities, and Sperm DNA Fragmentation. Jordan Journal of Biological SciencesReproductive biology2010  Visit URL
Abdalla MY, Hassan IM, Mustafa NH, Tahtamouni LH, Ahmad IM. (2010) Total Body Glutathione Depletion Induces Oxidative Stress and Disrupts the Immune Function in Mice. Toxicological & Environmental ChemistryCancer Research2010  Visit URL
Ahmad IM, Mustafa IH, Mustafa NH, Tahtamouni LH, Abdalla MY. (2010) 2-Deoxy-D-Glucose Enhances the Susceptibility of Breast Cancer Cells to Doxorubicin-induced Metabolic Oxidative Damage. Central European Journal of Biology Cancer Research2010  Visit URL
Tahtamouni LH, Wahdan RA, Elkarmi AZ. (2009) Sperm Chromatin Abnormalities Evaluated by Acridine Orange Staining Effect Developmental Rate and Embryo Quality. Jordan Journal of Biological Sciences Reproductive biology2009  Visit URL
Tahtamouni LH, Mustafa NH, Alfaouri AA, Hassan IM, Abdalla MY, Yasin SR. (2008) Prevalence and Risk Factors for Anabolic-Androgenic Steroid Abuse among Jordanian Collegiate Students and Athletes. European Journal of Public HealthReproductive biology2008  Visit URL
Kile BT, Panopoulos AD, Stirzaker RA, Hacking DF, Tahtamouni LH, Willson TA, Mielke LA, Henley KJ, Zhang J-G, Wicks IP, Stevenson WS, Nurden P, Watowich SS, Justice MJ. (2007) Mutations in the cofilin partner Aip1/Wdr1 cause autoinflammatory disease and macrothrombocytopenia. Blood Cancer research2007  Visit URL
Al-Qaisi KH, Elkarmi A, Qnais E, Tahtamouni L, Abu-Samak M. (2006) Allometry of postnatal rat brain development prenatally exposed to aspirin. Pakistan Journal of Biological Sciences Allometry2006  Visit URL
Kamel A, Qnais E, Khoury F, Tahtamouni LH, Massadeh M, Al-Matubsi H, Ghalyun YA. (2006) Reptilian skeletal muscle: physiological and fine structure properties of musculus iliofibularis of the lizard Chamaeleo chamaeleo recticrista.Proc Fourth Internat Conf Biol Sci Animal Physiology2006  Visit URL
Tahtamouni LH, Al- Hajj HA, Bata MS. (2002) Evaluation of etiological factors among 702 Jordanian infertile couples. Middle East Fertility Society Journal Reproductive Biology2002  Visit URL