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TAREQ NIZAR RASHAD SALEH
Faculty of Medicine
TAREQ NIZAR RASHAD SALEH
Faculty of Medicine
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Welcome to the Hashemite University faculty staff website.
Tareq Nizar Rashad Saleh
Associate Professor
Pharmacology and Toxicology
Pharmacology
Faculty of Medicine
Department of Pharmacology, Public Health and Clinical Skills
tareq@hu.edu.jo
ORCID ID :
228781107
Office No. :
5574
EXT :
5574
C.V. Document file as PDF:
Ph.D.
Virginia Commonwealth University
The United States of America,2018
Master
,
Bachelor
The Hashemite University
Jordan,2012
? The effects, biochemical and molecular mechanisms of anticancer drug combinations. ? Cancer cell stress response mechanisms. ? Involvement of autophagy in sensitivity and resistance to cytotoxic and targeted cancer therapy. ? The contribution of senescence to the anticancer therapy outcomes. ? The molecular and biochemical basis of therapy-induced senescence, tumor dormancy and recurrence. ? Novel uses of senolytic drugs for cancer prevention and treatment.
1. Saleh T, Tyutyunyk-Massey L, Gewirtz DA. Tumor Cell Escape from Therapy-Induced Senescence as a Model of Disease Recurrence after Dormancy. Cancer Res. 2019;79(6):1044–6. 2. Saleh T, Tyutyunyk-Massey L, Murray GF, Alotaibi MR, Kawale AS, Elsayed Z, et al. Tumor cell escape from therapy-induced senescence. Biochem Pharmacol. 2019;162:202–12. 3. Xu J, Patel NH, Saleh T, Cudjoe EK, Alotaibi M, Wu Y, et al. Differential Radiation Sensitivity in p53 WildType and p53-Deficient Tumor Cells Associated with Senescence but not Apoptosis or (Nonprotective) Autophagy. Radiat Res. 2018;190(5):538–57. 4. Saleh T, Tyutyunyk-Massey L, Cudjoe EK, Idowu MO, Landry JW, Gewirtz DA. Non-Cell Autonomous Effects of the Senescence-Associated Secretory Phenotype in Cancer Therapy. Front Oncol. 2018;8(164):1–14. 5. Cudjoe EK, Saleh T, Hawkridge AM, Gewirtz DA. Proteomics Insights into Autophagy. Proteomics. 2017;17(20). 6. Dajani R, Li J, Wei Z, March ME, Xia Q, Khader Y, et al. Genome-wide association study identifies novel type II diabetes risk loci in Jordan subpopulations. PeerJ. 2017;5:e3618. 7. Saleh T, Cuttino L, Gewirtz DA. Autophagy is not uniformly cytoprotective: a personalized medicine approach for autophagy inhibition as a therapeutic strategy in non-small cell lung cancer. Biochim Biophys Acta. 2016;1860(10):2130–6. 8. Alotaibi M, Sharma K, Saleh T, Povirk LF, Hendrickson EA, Gewirtz DA. Radiosensitization by PARP Inhibition in DNA Repair Proficient and Deficient Tumor Cells?: Proliferative Recovery in Senescent Cells. Radiat Res. 2016;185(3):229–45
American Association for Cancer Research
General Pharmacology (111501203) Hematopoietic System (181501207) Anticancer Pharmacology
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