Walaa Bayomie Abdulwahhab Elgazzar

walaa bayoumie abdulwahhab el gazzar	Associate Professor
medical biochemistry and molecular biology	Medical Biochemistry
Faculty of Medicine	Department of Anatomy, Physiology and Biochemistry
wallagazzar@hu.edu.jo
ORCID ID : 151721105
Office No. : 3032	EXT : 5416

C.V. Document file as PDF:

Ph.D.	benha	Egypt,2014
Master	benha	Egypt,2010
Bachelor	benha	Egypt,2004

molecular basis of diseases

 1.	El Gazzar, W. B., Sliem, R. E., Bayoumi, H., Nasr, H. E., Shabanah, M., Elalfy, A., Radwaan, S. E., Gebba, M. A., Mansour, H. M., Badr, A. M., Amer, M. F., Ashour, S. S., Morsi, H., Aboelkomsan, E. S. A. F., Baioumy, B., Sayed, A. E. H., & Farag, A. A. (2023). Melatonin Alleviates Intestinal Barrier Damaging Effects Induced by Polyethylene Microplastics in Albino Rats. International journal of molecular sciences, 24(17), 13619. https://doi.org/10.3390/ijms241713619
2.	El Gazzar, W. B., Albakri, K. A., Hasan, H., Badr, A. M., Farag, A. A., & Saleh, O. M. (2023). Poly(ADP-ribose) polymerase inhibitors in the treatment landscape of triple-negative breast cancer (TNBC). Journal of oncology pharmacy practice: official publication of the International Society of Oncology Pharmacy Practitioners, 29(6), 1467–1479. https://doi.org/10.1177/10781552231188903
3.	Shaimaa Nasr Amin, Fida Asali, Iman Aolymat, Dua Abuquteish, Ola Abu Al Karsaneh, Walaa Bayoumie El Gazzar, Sherif Ahmed Shaltout, Yasmeen Jamal Alabdallat, Dalia Azmy Elberry, Samaa Samir Kamar, Sara Adel Hosny, Marwa Nagi Mehesen, Laila Ahmed Rashed, Ayman Mohamed Farag & Asmaa Mohammed ShamsEldeen (2023) Comparing MitoQ10 and heat therapy: Evaluating mechanisms and therapeutic potential for polycystic ovary syndrome induced by circadian rhythm disruption, Chronobiology International, DOI: 10.1080/07420528.2023.2241902
4.	Farag, A. A., Youssef, H. S., Sliem, R. E., El Gazzar, W. B., Nabil, N., Mokhtar, M. M., Marei, Y. M., Ismail, N. S., Radwaan, S. E., Badr, A. M., & Sayed, A. E. H. (2023). Hematological consequences of polyethylene microplastics toxicity in male rats: Oxidative stress, genetic, and epigenetic links. Toxicology, 492, 153545. https://doi.org/10.1016/j.tox.2023.153545
5.	Allam, M., Anwer, H., EL Gazzar, W., Ahmed, N., El-shaer, N. Probiotic Lactobacillus Acidophilus prevents bone loss in aged osteoporosis in rats; the possible implication of NLRP3 Inflammasome. Bulletin of Egyptian Society for Physiological Sciences, 2023; 43(3): 171-187. doi: 10.21608/besps.2023.206894.1141
6.	Amin SN, Asali F, Elrefai MF, El Gazzar WB, Shaltout SA, Elberry DA, Kamar SS, Abdel Latif NS,  Mehesen MN, Ayoub MM, Albakri KA, ShamsEldeen AM. Insight Towards Induction of Reproductive-Metabolic Phenotypes of Polycystic Ovarian Syndrome. Jordan Journal of Biological Sciences. 2022; 15(5): 813 – 824.
7.	El Gazzar, W. B., Allam, M. M., Shaltout, S. A., Mohammed, L. A., Sadek, A. M., & Nasr, H. E. (2022). Pioglitazone modulates immune activation and ameliorates inflammation induced by injured renal tubular epithelial cells via PPAR?/miRNA 124/STAT3 signaling. Biomedical reports, 18(1), 2. https://doi.org/10.3892/br.2022.1584

8.	Amin SN, Sakr HI, El Gazzar WB, Shaltout SA, Ghaith HS, Elberry DA. Combined saline and vildagliptin induced M2 macrophage polarization in hepatic injury induced by acute kidney injury. PeerJ. 2023 Feb 13;11:e14724. doi: 10.7717/peerj.14724. PMCID: PMC9933746.
9.	Saleh, O. M., Albakri, K. A., Alabdallat, Y. J., Dajani, M. H., & El Gazzar, W. B. (2022). The safety and efficacy of CAR-T cells in the treatment of prostate cancer: review. Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals, 27(1), 22–34. https://doi.org/10.1080/1354750X.2021.2016973
10.	El-Shaer NO, El Gazzar WB, Allam MM, Anwer HM. Ghrelin ameliorated inflammation and oxidative stress in isoproterenol induced myocardial infarction through the endothelial nitric oxide synthase (eNOS)/nuclear factor erythroid 2-related factor-2 (NRF2)/heme oxygenase-1 (HO-1) signaling pathway. J Physiol Pharmacol. 2021 Apr;72(2). doi: 10.26402/jpp.2021.2.12. Epub 2021 Jul 10. PMID: 34642258.
11.	Allam MM, Ibrahim RM, El Gazzar WB, Said MA. Dipeptedyl peptidase-4 (DPP-4) inhibitor downregulates HMGB1/TLR4/NF-?B signaling pathway in a diabetic rat model of non-alcoholic fatty liver disease. Arch Physiol Biochem. 2021 Sep 20:1-9. doi: 10.1080/13813455.2021.1975758. Epub ahead of print. PMID: 34543583.
12.	Amin SN, Khashaba AS, Latif NSA, El Gazzar WB, Hussein UK. Citicoline improved cardiovascular function in animal model of dysautonomia. J Physiol Pharmacol. 2021 Feb;72(1). doi: 10.26402/jpp.2021.1.07. Epub 2021 Jun 3. PMID: 34099586.
13.	Amin SN, Abdalgeleel SA, Algahtany MA, Shaltout SA, El Gazzar WB, Elberry DA. Effect of Allopregnanolone on Spatial Memory and Synaptic Proteins in Animal Model of Metabolic Syndrome. Brain Sciences. 2021; 11(5):644.
14.	Elmadawy MA, Abdullah OA, El Gazzar WB, Ahmad ES, Ameen SG, Abdelkader A. Telomere length and signal joint T-cell receptor rearrangement excision circles as biomarkers for chronological age estimation. Biomarkers. 2021 Mar;26(2):168-173. doi: 10.1080/1354750X.2020.1871412. Epub 2021 Jan 21. PMID: 33401959.
15.	Abdullah OA, El Gazzar WB, Salem TI, Al-Kamil EA. Role of extracellular matrix remodelling gene SNPs in keratoconus. Br J Biomed Sci. 2020 Jan;77(1):13-18. doi: 10.1080/09674845.2019.1654346. Epub 2019 Aug 29. PMID: 31397194.
16.	Abdullah OA, El Gazzar WB, Salem TI, Elmohamady MN, Nasif SN, Eltaher SM. miR-15a: a potential diagnostic biomarker and a candidate for non-operative therapeutic modality for age-related cataract. Br J Biomed Sci. 2019 Oct;76(4):184-189. doi: 10.1080/09674845.2019.1639337. Epub 2019 Aug 14. PMID: 31264507.
17.	Madboly AG, Alhusseini NF, Abd El Rahman SM, El Gazzar WB, Idris AMM. Serum miR-122 and miR-192 as biomarkers of intrinsic and idiosyncratic acute hepatotoxicity: A quantitative real-time polymerase chain reaction study in adult albino rats. J Biochem Mol Toxicol. 2019 Jul;33(7): e22321. doi: 10.1002/jbt.22321. Epub 2019 Mar 29. PMID: 30925002.
18.	Ebrahim N, Ahmed IA, Hussien NI, Dessouky AA, Farid AS, Elshazly AM, Mostafa O, Gazzar WBE, Sorour SM, Seleem Y, Hussein AM, Sabry D. Mesenchymal Stem Cell-Derived Exosomes Ameliorated Diabetic Nephropathy by Autophagy Induction through the mTOR Signaling Pathway. Cells. 2018 Nov 22;7(12):226. doi: 10.3390/cells7120226. PMID: 30467302; PMCID: PMC6315695.
19.	Allam MM, El Gazzar WB. Exendin-4, a glucagon-like peptide-1 receptor agonist downregulates hepatic receptor for advanced glycation end products in non-alcoholic steatohepatitis rat model. Arch Physiol Biochem. 2018 Feb;124(1):10-17. doi: 10.1080/13813455.2017.1348362. Epub 2017 Jul 11. PMID: 28696785.
20.	InasA., Walaa B., Hammouda S., Taghreed A. and Iman M. (2018): MIR-143 AND STEMNESS MARKERS: CLINICAL AND PATHOLOGICAL IMPLICATIONS IN BLADDER CANCER, Arab. J. Lab. Med. Vol. 43, No. 2 : 337- 351
21.	Walaa B., Shaymaa M., Mohamed N., Ahmed M., Usama S. (2017): The -863 TNF-? Polymorphism and Primary Open Angle Glaucoma in Egyptians, American Journal of Biochemistry and Biotechnology, 13 (2): 85.89 DOI: 10.3844/ajbbsp.2017.85.89
22.	Naglaa F, Mosaad M, Mohammed A, Walaa B, Amr A (2010): Expression of Adiponectin Receptors in Human Placenta and Its Possible Implication in Gestational Diabetes. American Journal of Biochemistry and Biotechnology 6 (2): 136-140.

1- The effect of telomerase inhibition on Alpha-Fetoprotein expression in hepatocellular
carcinoma cell line.
2-ENDOCAN : a potential biomarker in Rheumatoid Arthritis, systemic sclerosis and
Behçet's disease.

 
2006to2010	
Demonstrator,BenhaUniversity,facultyofmedicine,MedicalBiochemistryandMolecularBiologydepartment.

2010to2014	
Lecturer,BenhaUniversity,facultyofmedicine,MedicalBiochemistryandMolecularBiologydepartment.

2014-2016	
Assistant Professor, BenhaUniversity,facultyofmedicine,MedicalBiochemistryandMolecularBiologydepartment.
2016-2020	
AssistantProfessor, Basic medical sciences department,Facultyof Medicine,Hashemite university,Jordan
2020 till present	
AssociateProfessor, Department of anatomy, physiology and biochemistry,Faculty of Medicine,Hashemite university,Jordan

 Genetics & Molecular Biology
General Biochemistry
Molecular Biology and Histology
(Molecular Biology)
Neuroscience I (Biochemistry)
Genito –Urinary
(Biochemistry)
Hematopoietic System (Biochemistry)
Cardiovascular system
(Biochemistry)
Respiratory system
(Biochemistry)
CHO, lipid and protein chemistry
CHO, lipid and protein metabolism

Genetics & Molecular Biology
General Biochemistry
Molecular Biology and Histology
(Molecular Biology)
Neuroscience I (Biochemistry)
Genito –Urinary
(Biochemistry)
Hematopoietic System (Biochemistry)
Cardiovascular system
(Biochemistry)
Respiratory system
(Biochemistry)
CHO, lipid and protein chemistry
CHO, lipid and protein metabolism

Walaa Bayomie Abdulwahhab Elgazzar

Walaa Bayomie Abdulwahhab Elgazzar

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